Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 1.00 |
| ▸ | RARG | P13631 | 11/20 | 1.00 |
| ▸ | RARA | P10276 | 7/20 | 1.00 |
| ▸ | CYP26A1 | O43174 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CRABP2 | P29373 | 1/20 | 1.00 |
| ▸ | RXRA | P19793 | 12/20 | 0.66 |
| ▸ | RXRB | P28702 | 10/20 | 0.66 |
| ▸ | RXRG | P48443 | 6/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302926 | 1.00 | RARB (1.00) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL8776480 | 0.91 | RARB (0.83) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7715323 | 0.89 | RARB (0.80) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL19697334 | 0.88 | RARB (0.78) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL29353991 | 0.87 | RARB (0.77) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL31046815 | 0.87 | RARB (0.77) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL20587536 | 0.87 | RARB (0.77) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL9484455 | 0.87 | RARB (0.76) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL7746407 | 0.86 | RARB (0.76) | RARBRARGRARACYP26A1CYP3A4 | |
| SCHEMBL6373022 | 0.86 | RARB (0.75) | RARBRARGRARACYP26A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 478 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713433-A2 | LIVER ORGANOIDS WITH INTRAHEPATIC SYMPATHETIC NERVES, AND METHODS OF USE THEREOF | Children's Hospital Medical Center (US) | 2026-03-25 | — | — | EP | claimed |
| EP-4689067-A2 | CLINICAL-GRADE ORGANOIDS | Children's Hospital Medical Center (US) | 2026-02-11 | — | — | EP | claimed |
| US-20260009005-A1 | GENERATING DORSAL FOREGUT, AND ANTERIOR DOMAIN, ENDODERM CELLS | THE CLEVELAND CLINIC FOUNDATION | 2026-01-08 | — | — | US | claimed |
| US-20260002121-A1 | IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES | CHILDRENS HOSPITAL MED CT (US) | 2026-01-01 | — | — | US | claimed |
| US-12435315-B2 | Generating dorsal foregut, and anterior domain, endoderm cells | THE CLEVELAND CLINIC FOUNDATION (US) | 2025-10-07 | — | — | US | claimed |
| US-20250304916-A1 | METHODS AND COMPOSITIONS FOR GENERATING VASCULAR LEPTOMENINGEAL CELLS | TRAILHEAD BIOSYSTEMS INC (US) | 2025-10-02 | — | — | US | claimed |
| EP-4606888-A1 | NOVEL PRODUCTION METHOD FOR NEURAL STEM CELL/NEURAL PROGENITOR CELL | K Pharma, Inc. (JP) | 2025-08-27 | — | — | EP | claimed |
| EP-4577639-A1 | METHODS AND COMPOSITIONS FOR SMALL MOLECULE BASED PANCREATIC BETA CELL INDUCTION | Trailhead Biosystems Inc. (US) | 2025-07-02 | — | — | EP | claimed |
| EP-4577641-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEMOGENIC ENDOTHELIAL CELLS FROM PLURIPOTENT STEM CELLS | Trailhead Biosystems Inc. (US) | 2025-07-02 | — | — | EP | claimed |
| EP-4569090-A2 | METHODS AND COMPOSITIONS FOR GENERATING OLIGODENDROCYTE PROGENITOR CELLS | Trailhead Biosystems Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| US-20220184012-A1 | RECEPTOR SUBTYPE AND FUNCTION SELECTIVE RETINOID AND REXINOID COMPOUNDS IN COMBINATION WITH IMMUNE MODULATORS FOR CANCER IMMUNOTHERAPY | Io Therapeutics, Inc. | 2022-06-16 | — | — | US | claimed |
| CN-114430774-A | Organoid mesoderm lineage diversification | 儿童医院医学中心 | 2022-05-03 | — | — | CN | claimed |
| CN-216412309-U | Wireless networking type fire audible and visual alarm | 浙江巨感物联网科技有限公司 | 2022-04-29 | — | — | CN | claimed |
| WO-2022051847-A9 | METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY | UNIVERSITY HEALTH NETWORK (CA) | 2022-04-21 | — | — | WO | claimed |
| US-20220106547-A1 | COMPOSITIONS AND METHODS OF USING PARTIAL GEL LAYERS IN A MICROFLUIDIC DEVICE | EMULATE INC (US) | 2022-04-07 | — | — | US | claimed |
| EP-3972990-A1 | GENERATING DORSAL FOREGUT, AND ANTERIOR DOMAIN, ENDODERM CELLS | The Cleveland Clinic Foundation (US) | 2022-03-30 | — | — | EP | claimed |
| WO-2022051847-A1 | METHODS FOR GENERATING NEURAL PROGENITOR CELLS WITH A SPINAL CORD IDENTITY | UNIVERSITY HEALTH NETWORK (CA) | 2022-03-17 | — | — | WO | claimed |
| EP-3967299-A1 | PKC ACTIVATORS AND COMBINATIONS THEREOF | Cognitive Research Enterprises, Inc. (US) | 2022-03-16 | — | — | EP | claimed |
| EP-3965934-A1 | COMPOSITIONS AND METHODS OF USING PARTIAL GEL LAYERS IN A MICROFLUIDIC DEVICE | Emulate, Inc. (US) | 2022-03-16 | — | — | EP | claimed |
| CN-114096557-A | Generation of germ layer cells in the dorsal foregut and anterior structural domains | 克利夫兰诊所基金会 | 2022-02-25 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260009005-A1 | GENERATING DORSAL FOREGUT, AND ANTERIOR DOMAIN, ENDODERM CELLS | BMP4, BMPR2, DACH1 | RARB 19/4885RARG 28/4885RARA 32/4885 |
| US-20220184012-A1 | RECEPTOR SUBTYPE AND FUNCTION SELECTIVE RETINOID AND REXINOID COMPOUNDS IN COMBINATION WITH IMMUNE MODULATORS FOR CANCER IMMUNOTHERAPY | RXRA, RXRG, RXRB | RARB 5/4885RARG 4/4885RARA 6/4885 |
| US-20260002121-A1 | IMPROVED METHODS OF PREPARING DIFFERENT MESODERM CELL TYPES | BMP4, RARB, WNT3A | RARB 2/4885RARG 5/4885RARA 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.