Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562323 | 0.90 | PDE4A (0.40) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL10562924 | 0.89 | CES2 (0.36) | MEN1KMT2AMAPTACHEKDM4E | |
| SCHEMBL10560355 | 0.89 | HTT (0.38) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL7286210 | 0.88 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10559039 | 0.88 | KMT2A (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL10557556 | 0.88 | MAPT (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10556208 | 0.88 | MAPT (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL9601585 | 0.88 | MIF (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10561260 | 0.88 | ACHE (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL10561166 | 0.87 | GAA (0.36) | MEN1KMT2AMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843075-A | ANXIOLYTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | claimed |
| EP-0252990-A1 | BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | claimed |
| WO-1998009969-A1 | NOVEL ARYL-PYRIDAZINES | ASTRA PHARMACEUTICALS LTD. (GB) | 1998-03-12 | — | — | WO | disclosed |
| US-4843075-A | ANXIOLYTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0252990-A1 | BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |