Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707482 | 0.89 | HTR2C (0.38) | ELANEF2CTSGHTR2CTACR1 | |
| SCHEMBL7542146 | 0.70 | NPC1 (0.43) | CASP1HTR2CMGAT2TACR1GRM5 | |
| SCHEMBL16539832 | 0.67 | HTR2C (0.43) | HTR2C | |
| SCHEMBL8067334 | 0.67 | TACR1 (0.57) | TACR1 | |
| SCHEMBL29661999 | 0.67 | TACR1 (0.57) | TACR1 | |
| SCHEMBL5783726 | 0.65 | GNRHR (0.43) | GNRHRKCNH2HTR2C | |
| SCHEMBL1670310 | 0.64 | HTR2C (0.49) | HTR2CTACR1 | |
| SCHEMBL5600502 | 0.64 | GNRHR (0.47) | GNRHRKCNH2HTR2C | |
| Alcohol SCHEMBL27541427 | 0.64 | TSHR (0.53) | PKMHTR2C | |
| Hydrochloric Acid SCHEMBL8814693 | 0.64 | BACE1 (0.45) | HTR2CTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025605-A1 | SPIRO-SUBSTITUTED AZACYCLES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | MERCK & CO., INC. (US) | 1998-06-18 | — | — | WO | claimed |