Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20587580 | 0.84 | ERAP1 (0.47) | MAPTKDM4ERECQLGAAPOLB | |
| SCHEMBL1255490 | 0.79 | MEN1 (0.48) | MAPTKDM4ERECQLGAAPOLB | |
| SCHEMBL27844788 | 0.76 | GAA (0.52) | MAPTKDM4ERECQLGAAPOLB | |
| SCHEMBL28143419 | 0.76 | KDM4E (0.56) | MAPTKDM4EPKMMEN1KMT2A | |
| SCHEMBL20587781 | 0.75 | KDM4E (0.48) | MAPTKDM4ERECQLGAAPOLB | |
| Methane SCHEMBL29191891 | 0.74 | GAA (0.50) | MAPTKDM4ERECQLGAAPOLB | |
| SCHEMBL9749884 | 0.74 | LMNA (0.50) | MAPTKDM4ERECQLGAAPOLB | |
| SCHEMBL11479865 | 0.73 | CYP3A4 (0.58) | MAPTKDM4ERECQLGAAPKM | |
| SCHEMBL471861 | 0.73 | MEN1 (0.71) | MAPTKDM4ERECQLGAAPKM | |
| SCHEMBL5084165 | 0.72 | ABCB1 (0.75) | MAPTKDM4ERECQLPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106974907-A | A kind of application of 4 aryl-coumarin class compound | 山东省医学科学院药物研究所 | 2017-07-25 | — | — | CN | disclosed |
| WO-1998025608-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING A 4-ARYLCOUMARIN FOR THE TREATMENT OF VIRAL INFECTIONS | BIO'S S.R.L. (IT) | 1998-06-18 | — | — | WO | disclosed |