Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676342 | 0.84 | KMT2A (0.58) | MEN1KMT2AKDM4EMAPTRECQL | |
| SCHEMBL1607111 | 0.82 | MEN1 (0.62) | MEN1KMT2AKDM4EMAPTPKM | |
| SCHEMBL31344371 | 0.82 | MEN1 (0.62) | MEN1KMT2AKDM4EMAPTPKM | |
| SCHEMBL23459097 | 0.81 | MAOA (0.56) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL16827005 | 0.81 | MGAM (0.51) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL31344370 | 0.81 | MGAM (0.51) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL8580811 | 0.79 | MAPT (0.46) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL471861 | 0.79 | MEN1 (0.71) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL27322035 | 0.78 | FLT3 (0.64) | MEN1KMT2AKDM4EMAPTGAA | |
| SCHEMBL10324199 | 0.77 | MGAM (0.56) | MEN1KMT2AKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 813 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3699174-B1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | ILAB (KR) | 2025-11-12 | — | — | EP | claimed |
| CN-119015393-A | Collagen peptide composition for improving vascular elasticity and preparation method thereof | 山东隆贝生物科技有限公司 | 2024-11-26 | — | — | CN | claimed |
| US-11850230-B2 | Composition for preventing or treating TNF-related diseases, containing novel derivative as active ingredient, and method for inhibiting TNF activity by using same | ILAB (KR) | 2023-12-26 | — | — | US | claimed |
| US-20230099574-A1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING NOVEL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | ILAB (KR) | 2023-03-30 | — | — | US | claimed |
| CN-113908147-A | Application of 7,8,4 '-trihydroxyisoflavone and anti-haze preparation containing 7,8, 4' -trihydroxyisoflavone | 高雄医学大学 | 2022-01-11 | — | — | CN | claimed |
| CN-113512018-A | Flavonoid compound and preparation method and application thereof | 合肥工业大学 | 2021-10-19 | — | — | CN | claimed |
| CN-113475635-A | Additive premix for relieving oxidative stress of sows | 广东省农业科学院动物科学研究所 | 2021-10-08 | — | — | CN | claimed |
| CN-112136980-A | Additive premix for improving sow production performance | 广东省农业科学院动物科学研究所 | 2020-12-29 | — | — | CN | claimed |
| EP-3699174-A1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING NOVEL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | ILAB (KR) | 2020-08-26 | — | — | EP | claimed |
| CN-111574490-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-25 | — | — | CN | claimed |
| US-20040209825-A1 | Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto | LAHEY THOMAS P (US) | 2004-10-21 | — | — | US | claimed |
| CN-1141092-C | Composition for preventing and treating osteoporosis and cancer and decreasing blood fat and its application | 郭兴华 | 2004-03-10 | — | — | CN | claimed |
| CN-1475488-A | Fluoro isoflavone containing derivative, monufacturing method and its use | 东华大学 | 2004-02-18 | — | — | CN | claimed |
| CN-1424030-A | Medicines for preventing and treating retina and cornea blood vessel diseases | UNIV NANJING MEDICAL (CN) | 2003-06-18 | — | — | CN | claimed |
| WO-2002074278-A1 | TOPICAL COMPOSITION CONTAINING AN ASSOCIATION OF AVOCADO FURANE LIPIDS AND ISOFLAVONES | LABORATOIRES EXPANSCIENCE (FR) | 2002-09-26 | — | — | WO | claimed |
| EP-1189897-A1 | ISOFLAVONE METABOLITES | G.J. Consultants Pty Ltd (AU) | 2002-03-27 | — | — | EP | claimed |
| CN-1306434-A | Composition for preventing and/or treating osteoporosis and pathologies resulting from menopausal syndrome | SIGMA TAU HEALTHSCIENCE SPA (IT) | 2001-08-01 | — | — | CN | claimed |
| CN-1304724-A | Composition for preventing and treating osteoporosis and cancer and decreasing blood fat and its application | GUO XINGHUA (CN) | 2001-07-25 | — | — | CN | claimed |
| WO-2000066576-A1 | ISOFLAVONE METABOLITES | G.J. CONSULTANTS PTY LTD (AU) | 2000-11-09 | — | — | WO | claimed |
| CN-1259130-A | Preparation of isoflavones from leguminous plants | NOVOGEN INC (US) | 2000-07-05 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11850230-B2 | Composition for preventing or treating TNF-related diseases, containing novel derivative as active ingredient, and method for inhibiting TNF activity by using same | TNF, NFKBIA, TRAF6 | MEN1 4570/4885KMT2A 4786/4885KDM4E 2226/4885 |
| US-20230099574-A1 | COMPOSITION FOR PREVENTING OR TREATING TNF-RELATED DISEASES, CONTAINING NOVEL DERIVATIVE AS ACTIVE INGREDIENT, AND METHOD FOR INHIBITING TNF ACTIVITY BY USING SAME | TNF, NFKBIA, TRAF6 | MEN1 4570/4885KMT2A 4786/4885KDM4E 2226/4885 |
| US-20040209825-A1 | Inhibition by 3-deoxyflavonoids of T-lymphocyte activation and therapies related thereto | HLA-DRB1, NFATC1, CD4 | MEN1 4047/4885KMT2A 3519/4885KDM4E 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.