Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18118643 | 0.97 | CYP3A4 (0.55) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL29038494 | 0.83 | MEN1 (0.63) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL29466790 | 0.79 | MAOB (0.70) | CYP3A4MEN1KMT2AALOX15KDM4E | |
| SCHEMBL669375 | 0.79 | MAOB (0.70) | CYP3A4MEN1KMT2AALOX15KDM4E | |
| SCHEMBL31457155 | 0.78 | MAOA (0.52) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL471846 | 0.78 | MAOA (0.52) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL1607111 | 0.77 | MEN1 (0.62) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL31344371 | 0.77 | MEN1 (0.62) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL11477475 | 0.75 | ADORA3 (0.53) | CYP3A4MEN1KMT2AMAPTALOX15 | |
| SCHEMBL7797188 | 0.75 | CA12 (0.48) | CYP3A4MEN1KMT2AMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230850-A | HYPOTENSIVE AGENTS, VASODILATION | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1980-10-28 | — | — | US | disclosed |