Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153194 | 0.91 | TDP1 (0.39) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL8579683 | 0.89 | ACACB (0.42) | TSHRTDP1MAPTRAB9AALDH1A1 | |
| SCHEMBL8581018 | 0.88 | TSHR (0.41) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL17660080 | 0.85 | TDP1 (0.46) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL8157894 | 0.83 | TDP1 (0.39) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL7613145 | 0.81 | RORC (0.52) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL8581071 | 0.78 | TSHR (0.50) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL8776923 | 0.78 | GAA (0.41) | TSHRTDP1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10712264 | 0.78 | MAPT (0.45) | TSHRTDP1SMN1; SMN2MAPTNPC1 | |
| SCHEMBL8582322 | 0.77 | SMN1; SMN2 (0.43) | TSHRTDP1SMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744203-A | POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |