Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24359640 | 0.88 | KDM4E (0.50) | MAPTALDH1A1POLBKDM4E | |
| SCHEMBL20352233 | 0.79 | KDM4E (0.43) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL18544756 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1POLBKDM4ELMNA | |
| SCHEMBL10040033 | 0.77 | MAPT (0.67) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL14190592 | 0.77 | POLB (0.38) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL2701173 | 0.77 | POLB (0.38) | MAPTALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL24359638 | 0.77 | MAPT (0.43) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL11453595 | 0.77 | KDM4E (0.38) | MAPTALDH1A1POLBKDM4E | |
| SCHEMBL18538905 | 0.74 | KDM4E (0.48) | MAPTALDH1A1POLBKDM4EGAA | |
| SCHEMBL4409107 | 0.72 | MAPT (0.68) | MAPTALDH1A1POLBKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811575-A | HEATING 2-CHLOROETHYLPHOSPHONIC ACIDS | CLARIANT GMBH (DE) | 1998-09-22 | — | — | US | disclosed |
| US-3972923-A | FROM AN ACYL HALIDE AND A PHOSPHONIC ACID DERIVATIVE | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |