Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580028 | 0.90 | PDGFRB (0.39) | HSD17B10PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL8580665 | 0.89 | PDGFRB (0.42) | PPARGPPARAHSD17B10PDGFRBFGFR1 | |
| SCHEMBL8578766 | 0.88 | PPARG (0.38) | PPARGPPARAHSD17B10FLT1KDR | |
| SCHEMBL8581893 | 0.87 | CA2 (0.47) | HSD17B10KDRLMNA | |
| SCHEMBL8583085 | 0.87 | PPARG (0.37) | PPARGPPARAHSD17B10FLT1KDR | |
| SCHEMBL8582974 | 0.84 | CDK1 (0.38) | HSD17B10PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL8585349 | 0.84 | PPARG (0.37) | PPARGPPARAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8580858 | 0.83 | CNR2 (0.37) | PPARGPPARAHSD17B10FLT1KDR | |
| SCHEMBL8583870 | 0.83 | SLC9A1 (0.41) | PPARGPPARAHSD17B10FLT1KDR | |
| SCHEMBL8585502 | 0.82 | CNR2 (0.41) | PPARGPPARAHSD17B10ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |