Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037585 | 1.00 | MMP9 (0.51) | MMP9GABRB1GABRB2CTSSCTSK | |
| SCHEMBL13715427 | 0.89 | MMP9 (0.59) | MMP9GABRB1GABRB2CTSSCTSK | |
| SCHEMBL6917355 | 0.85 | MMP9 (0.53) | MMP9METAP2METAP1MEN1KMT2A | |
| SCHEMBL5076750 | 0.85 | MMP9 (0.53) | MMP9METAP2METAP1MEN1KMT2A | |
| SCHEMBL8576836 | 0.85 | MMP9 (0.53) | MMP9METAP2METAP1MEN1KMT2A | |
| SCHEMBL8385834 | 0.85 | CTSK (0.54) | CTSSCTSKMEN1KMT2ACA2 | |
| SCHEMBL851252 | 0.83 | GABRB1 (0.52) | MMP9GABRB1GABRB2CTSSCTSK | |
| SCHEMBL6832916 | 0.83 | GABRB1 (0.52) | MMP9GABRB1GABRB2CTSSCTSK | |
| SCHEMBL11060442 | 0.82 | CTSK (0.53) | MMP9GABRB1GABRB2CTSSCTSK | |
| SCHEMBL8682582 | 0.81 | CTSK (0.49) | CTSSCTSKMEN1KMT2ACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847194-A | Carbamoylcarboxamides | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0778824-B1 | CARBAMOYL CARBOXYLIC ACID AMIDES | BASF AG (DE) | 1998-11-04 | — | — | EP | disclosed |