Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8579892 | 0.99 | CNR2 (0.42) | CNR2RARBRARARARGMEN1 | |
| SCHEMBL8582507 | 0.95 | CNR2 (0.38) | CNR2ALDH1A1TRPV1KDM4EHPGD | |
| SCHEMBL8583066 | 0.90 | PPARG (0.36) | CNR2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8581020 | 0.87 | CNR2 (0.41) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8580391 | 0.86 | CNR2 (0.40) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8583900 | 0.86 | CNR2 (0.40) | CNR2RARBMEN1ALDH1A1KMT2A | |
| SCHEMBL8581804 | 0.86 | CNR2 (0.41) | CNR2MEN1ALDH1A1KMT2AALOX5 | |
| SCHEMBL8583149 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL8580534 | 0.85 | ALDH1A1 (0.41) | CNR2ALDH1A1 | |
| SCHEMBL8581983 | 0.85 | PPARA (0.45) | CNR2MEN1ALDH1A1KMT2AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |