Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580706 | 0.99 | PPARA (0.43) | PPARAPPARGHTR2AALOX5PTGS2 | |
| SCHEMBL8581516 | 0.95 | HTT (0.40) | PPARAPPARGHTR2AALOX5CNR2 | |
| SCHEMBL8581020 | 0.87 | CNR2 (0.41) | PPARAPPARGALOX5PTGS2CNR2 | |
| SCHEMBL8583900 | 0.86 | CNR2 (0.40) | ALOX5CNR2MEN1ALDH1A1KMT2A | |
| SCHEMBL8580391 | 0.86 | CNR2 (0.40) | PPARAPPARGALOX5PTGS2CNR2 | |
| SCHEMBL8581804 | 0.86 | CNR2 (0.41) | ALOX5PTGS2CNR2MEN1ALDH1A1 | |
| SCHEMBL8581653 | 0.85 | HTT (0.45) | MEN1KMT2AHTT | |
| SCHEMBL8580534 | 0.85 | ALDH1A1 (0.41) | CNR2ALDH1A1 | |
| SCHEMBL8580983 | 0.85 | CNR2 (0.42) | ALOX5CNR2MEN1ALDH1A1KMT2A | |
| SCHEMBL8581001 | 0.85 | CA12 (0.41) | ALOX5CNR2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |