Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 4/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12975716 | 0.90 | MMEL1 (0.43) | MMEL1CTSSCTSKATMMME | |
| SCHEMBL14959406 | 0.90 | MMEL1 (0.43) | MMEL1CTSSCTSKATMMME | |
| SCHEMBL10198332 | 0.89 | MMEL1 (0.58) | MMEL1CTSSCTSKATMMME | |
| SCHEMBL15943065 | 0.89 | MMEL1 (0.45) | MMEL1ATMMMEPTPRB | |
| SCHEMBL12975711 | 0.85 | MME (0.52) | MMEL1CTSSCTSKATMMME | |
| SCHEMBL8552371 | 0.83 | MME (0.50) | MMEL1MMEACE | |
| SCHEMBL14952827 | 0.83 | MMEL1 (0.65) | MMEL1MME | |
| SCHEMBL12975292 | 0.83 | MMEL1 (0.65) | MMEL1MME | |
| SCHEMBL31258217 | 0.81 | CTSS (0.52) | CTSSCTSKACE | |
| SCHEMBL1912622 | 0.81 | CTSS (0.55) | MMEL1CTSSCTSKATMMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065958-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | NOVARTIS AG (CH) | 2012-05-24 | — | — | WO | disclosed |