Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581805 | 0.81 | CMA1 (0.43) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8529635 | 0.80 | SLC9A1 (0.39) | — | |
| SCHEMBL8582971 | 0.80 | KDM4E (0.37) | POLBALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL8582606 | 0.80 | KDM4E (0.37) | POLBALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL8585015 | 0.80 | KDM4E (0.37) | POLBALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL8579193 | 0.78 | KDM4E (0.36) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8581321 | 0.77 | TRPV1 (0.39) | VCAM1POLBALDH1A1TSHRKDM4E | |
| SCHEMBL8583140 | 0.76 | TRPV1 (0.40) | VCAM1POLBALDH1A1KDM4EHPGD | |
| SCHEMBL8583192 | 0.74 | CMA1 (0.40) | ALDH1A1TSHRKDM4EHPGDMAPT | |
| SCHEMBL8581247 | 0.73 | KDM4E (0.35) | POLBALDH1A1TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |