Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.82 |
| ▸ | GLO1 | Q04760 | 7/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.82 |
| ▸ | MEN1 | O00255 | 5/20 | 0.82 |
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.65 |
| ▸ | METAP2 | P50579 | 1/20 | 0.65 |
| ▸ | METAP1 | P53582 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979087 | 0.91 | TDP1 (1.00) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL442367 | 0.80 | SLC40A1 (1.00) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL1695444 | 0.80 | KDR (0.71) | TDP1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29851236 | 0.80 | KDR (0.71) | TDP1KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL23413185 | 0.80 | MEN1 (0.67) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL30092884 | 0.80 | MEN1 (0.67) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL7746129 | 0.79 | SLC40A1 (0.97) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL30925435 | 0.78 | SLC40A1 (0.74) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL16750883 | 0.78 | SLC40A1 (0.74) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL12964661 | 0.78 | SLC40A1 (0.75) | TDP1GLO1KMT2AMEN1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999029670-A2 | AMINOCARBONYLTETRALIN AND DIHYDRONAPHTALENE DERIVATES AS THROMBIN INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-17 | — | — | WO | disclosed |