Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 1.00 |
| ▸ | GLO1 | Q04760 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | MEN1 | O00255 | 6/20 | 1.00 |
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.74 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.74 |
| ▸ | G6PD | P11413 | 1/20 | 0.74 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.74 |
| ▸ | METAP2 | P50579 | 1/20 | 0.74 |
| ▸ | METAP1 | P53582 | 1/20 | 0.74 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.74 |
| ▸ | ATM | Q13315 | 1/20 | 0.74 |
| ▸ | PLAU | P00749 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MITF | O75030 | 1/20 | 0.69 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583772 | 0.91 | TDP1 (0.82) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL442367 | 0.85 | SLC40A1 (1.00) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL416258 | 0.84 | MEN1 (0.73) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL7746129 | 0.84 | SLC40A1 (0.97) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL13485937 | 0.84 | SLC40A1 (0.74) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL16750883 | 0.84 | SLC40A1 (0.74) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL30925435 | 0.84 | SLC40A1 (0.74) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL13485924 | 0.83 | GLO1 (0.84) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL11973786 | 0.83 | SLC40A1 (1.00) | TDP1GLO1KMT2AMEN1SLC40A1 | |
| SCHEMBL22076984 | 0.82 | MEN1 (1.00) | TDP1GLO1KMT2AMEN1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ZOETIS LLC | 2024-05-09 | — | — | US | disclosed |
| US-20240019450-A1 | FLUORESCENT SENSORS | THE UNIVERSITY OF SYDNEY (AU) | 2024-01-18 | — | — | US | disclosed |
| US-20240019450-A1 | FLUORESCENT SENSORS | THE UNIVERSITY OF SYDNEY (AU) | 2024-01-18 | — | — | US | disclosed |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-18 | — | — | US | disclosed |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-18 | — | — | US | disclosed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6528187-B1 | Luminescence element comprising pair of electrodes having formed therebetween plurality of organic compound thin film layers comprising electron-transporting layer which comprises specified compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148744-A1 | SULFONAMIDES AND THEIR USE FOR TREATMENT OF HELMINTHIC INFECTIONS AND DISEASES | ARSA, MRPS2, SULT2A1 | TDP1 4247/4885GLO1 3779/4885KMT2A 1323/4885 |
| US-20100041653-A1 | COMPOSITION AND METHODS FOR THE DESIGN AND DEVELOPMENT OF METALLO-ENZYME INHIBITORS | HELZ, MMEL1, GAA | TDP1 1854/4885GLO1 2965/4885KMT2A 764/4885 |
| US-20240019450-A1 | FLUORESCENT SENSORS | NCS1, TRPA1, AQP1 | TDP1 1733/4885GLO1 61/4885KMT2A 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.