Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583683 | 0.99 | SLC9A1 (0.40) | SLC9A1YAP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8581635 | 0.94 | SLC9A1 (0.41) | SLC9A1KDM4EALDH1A1MAPTSCN5A | |
| SCHEMBL8585114 | 0.92 | SLC9A1 (0.37) | SLC9A1YAP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8581550 | 0.90 | SLC9A1 (0.38) | SLC9A1YAP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8581975 | 0.89 | SCN9A (0.39) | SLC9A1KDM4EALDH1A1HSD17B10TSHR | |
| SCHEMBL8583098 | 0.85 | SLC9A1 (0.39) | SLC9A1KDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL8581253 | 0.85 | SLC9A1 (0.47) | SLC9A1YAP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8582631 | 0.84 | YAP1 (0.41) | SLC9A1YAP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8580817 | 0.84 | ALDH1A1 (0.42) | SLC9A1YAP1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8585515 | 0.84 | SCN9A (0.43) | SLC9A1YAP1ALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840761-A | Alkylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-11-24 | — | — | US | disclosed |