Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | FABP2 | P12104 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flufenamic Acid SCHEMBL21408198 | 0.88 | PTGS2 (0.69) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL49245 | 0.84 | METTL3 (0.83) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL9856559 | 0.84 | METTL3 (0.81) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL26088 | 0.84 | METTL3 (0.84) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL29483481 | 0.84 | METTL3 (0.84) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL20503838 | 0.83 | METTL3 (0.70) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL9445147 | 0.83 | METTL3 (0.70) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL7160746 | 0.83 | METTL3 (0.79) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL16760954 | 0.83 | METTL3 (0.79) | METTL3PTGS2AKR1C3AKR1C2TTR | |
| Terofenamate SCHEMBL1671593 | 0.83 | METTL3 (0.83) | METTL3PTGS2AKR1C3AKR1C2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0759750-A4 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1998-05-27 | — | — | EP | claimed |
| EP-0759750-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO, Howard, K. (US) | 1997-03-05 | — | — | EP | claimed |
| WO-1995031194-A1 | COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES | SHAPIRO HOWARD K (US) | 1995-11-23 | — | — | WO | claimed |