Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 9/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.32 |
| ▸ | PYGL | P06737 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8581721 | 0.88 | GHSR (0.48) | GHSRBACE1PYGLXIAP | |
| SCHEMBL8613091 | 0.84 | GHSR (0.40) | GHSRCYP3A4SCN9A | |
| SCHEMBL8580708 | 0.74 | GHSR (0.43) | GHSRBACE1 | |
| SCHEMBL5196233 | 0.73 | GHSR (0.61) | GHSRBACE1PYGL | |
| SCHEMBL8583068 | 0.72 | GHSR (0.43) | GHSR | |
| SCHEMBL2813574 | 0.71 | GHSR (0.63) | GHSRBACE1PYGL | |
| SCHEMBL18614234 | 0.71 | GHSR (0.63) | GHSRBACE1PYGL | |
| SCHEMBL29715495 | 0.71 | GHSR (0.63) | GHSRBACE1PYGL | |
| SCHEMBL8997810 | 0.70 | P2RY1 (0.39) | P2RY1 | |
| SCHEMBL8584168 | 0.70 | BUB1 (0.32) | GHSRP2RY1BACE1CYP3A4SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |