Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582291 | 0.88 | SYK (0.42) | GHSRALDH1A1HPGDHSD17B10 | |
| SCHEMBL8581721 | 0.82 | GHSR (0.48) | GHSRBACE1 | |
| SCHEMBL8580657 | 0.76 | GAA (0.36) | GAABACE1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8583068 | 0.76 | GHSR (0.43) | GHSR | |
| SCHEMBL8997611 | 0.76 | RPS6KA1 (0.34) | GHSRGAABACE1ALDH1A1KCNA5 | |
| SCHEMBL8585740 | 0.74 | GHSR (0.45) | GHSRBACE1 | |
| SCHEMBL8613152 | 0.72 | GHSR (0.36) | GHSROPRD1BACE1 | |
| SCHEMBL8997591 | 0.72 | GHSR (0.36) | GHSROPRD1BACE1 | |
| SCHEMBL5196233 | 0.71 | GHSR (0.61) | GHSRBACE1 | |
| SCHEMBL2813574 | 0.69 | GHSR (0.63) | GHSRBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837807-A | DIPEPTIDES AND CYCLIC PEPTIDE DERIVATIVES OF AMINO TETRAHYDRONAPHTHALENECARBOXYLIC ACID AND HELICAL DOMAINS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-17 | — | — | US | disclosed |