Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584601 | 0.91 | ALOX5 (0.35) | ALOX5PTGS2PTGS1ALDH1A1LMNA | |
| SCHEMBL8584611 | 0.89 | HMGCR (0.35) | HMGCRNR1I2LMNAMAPT | |
| SCHEMBL8583640 | 0.88 | HMGCR (0.35) | HMGCRALOX5PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8585200 | 0.87 | HMGCR (0.32) | HMGCRNR1I2ALOX5PTGS2PTGS1 | |
| SCHEMBL7120195 | 0.84 | HMGCR (0.43) | HMGCRNR1I2ALOX5PTGS2PTGS1 | |
| SCHEMBL7129122 | 0.83 | HMGCR (0.38) | HMGCRNR1I2ALOX5PTGS2PTGS1 | |
| SCHEMBL8584333 | 0.77 | NOTUM (0.36) | ALOX5PTGS2PTGS1ALDH1A1MAPT | |
| SCHEMBL7119797 | 0.77 | NOTUM (0.39) | ALOX5PTGS2PTGS1ALDH1A1MAPT | |
| SCHEMBL8611255 | 0.74 | ALOX5 (0.43) | HMGCRNR1I2ALOX5PTGS2PTGS1 | |
| SCHEMBL7130009 | 0.73 | KCNA5 (0.39) | ALDH1A1LMNATP53MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028312-A1 | PHARMACEUTICAL AMINOPHOSPHONIC ACID DERIVATIVES | SYMPHAR S.A. (CH) | 1998-07-02 | — | — | WO | claimed |