Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120195 | 0.89 | HMGCR (0.43) | ALOX5PTGS2PTGS1KCNA5LMNA | |
| SCHEMBL8612757 | 0.88 | HMGCR (0.42) | ALOX5PTGS2PTGS1KCNA5LMNA | |
| SCHEMBL7128467 | 0.87 | ALOX5 (0.46) | ALOX5PTGS2PTGS1KCNA5LMNA | |
| SCHEMBL7129895 | 0.84 | ERN1 (0.41) | KCNA5LMNAALDH1A1MAPTALOX15 | |
| SCHEMBL8584601 | 0.84 | ALOX5 (0.35) | ALOX5PTGS2PTGS1KCNA5LMNA | |
| SCHEMBL7129122 | 0.83 | HMGCR (0.38) | ALOX5PTGS2PTGS1KCNA5LMNA | |
| SCHEMBL8609257 | 0.74 | HMGCR (0.43) | ALOX5PTGS2PTGS1LMNAALDH1A1 | |
| SCHEMBL7119084 | 0.74 | ERN1 (0.39) | KCNA5LMNAALDH1A1MAPTALOX15 | |
| SCHEMBL8766643 | 0.74 | HMGCR (0.48) | PTGS2LMNAALDH1A1MAPTMAPK1 | |
| SCHEMBL8586262 | 0.74 | HMGCR (0.35) | ALOX5PTGS2PTGS1KCNA5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835116-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1998-04-15 | — | — | EP | claimed |
| WO-1997002037-A1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SYMPHAR S.A. (CH) | 1997-01-23 | — | — | WO | claimed |