SCHEMBL8586265

SCHEMBL8586265

OC(c1cc(C(O)(C(F)(F)F)C(F)(F)F)cc(C(O)(C(F)(F)F)C(F)(F)F)c1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 11/20 0.48
NR1H3 Q13133 11/20 0.48
AR P10275 1/20 0.43
MEN1 O00255 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MLYCD O95822 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
RORA P35398 1/20 0.38
RORC P51449 1/20 0.38
PGR P06401 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11884233 0.91 CES2 (0.48) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL10212933 0.89 GABRA1 (0.46) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL23059982 0.87 GABRA1 (0.50) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL10878498 0.87 NR1H2 (0.40) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL12370803 0.87 NR1H2 (0.40) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL10215034 0.87 MLYCD (0.48) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL19718366 0.87 GABRA1 (0.50) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL11049553 0.84 NR1H2 (0.39) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL7812223 0.83 NR1H2 (0.41) NR1H2NR1H3ARMEN1ALOX15
SCHEMBL832913 0.83 NR1H3 (0.47) NR1H2NR1H3ARMEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0681713-B1 SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE CLARIANT GMBH (DE) 1998-11-18 EP disclosed
US-5716756-A POSITIVE OR NEGATIVE WORKING MIXTURES HOECHST AKTIENGESELLSCHAFT (DE) 1998-02-10 US disclosed
EP-0681713-A1 SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-11-15 EP disclosed
WO-1994018606-A1 SULPHONIC ACID ESTERS, RADIATION-SENSITIVE MIXTURES MADE THEREWITH, AND THEIR USE HOESCHT AKTIENGESELLSCHAFT (DE) 1994-08-18 WO disclosed