Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 7/20 | 0.51 |
| ▸ | CA9 | Q16790 | 7/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8147467 | 0.95 | CA1 (0.56) | CA12CA1CA9CA2CYP3A4 | |
| SCHEMBL8585276 | 0.86 | ALDH1A1 (0.40) | CA12CA1CA9CA2GRIA4 | |
| SCHEMBL7570581 | 0.86 | CA12 (0.43) | CA12CA1CA9CA2GRIA4 | |
| SCHEMBL8584809 | 0.86 | MAOB (0.44) | CA12CA1CA9CA2GRIA4 | |
| SCHEMBL8587469 | 0.85 | KIF11 (0.51) | CA1CA2MEN1KMT2AKIF11 | |
| SCHEMBL8585567 | 0.85 | L3MBTL1 (0.43) | CA12CA1CA9CA2CYP3A4 | |
| SCHEMBL8583844 | 0.84 | KIF11 (0.46) | CYP3A4ALDH1A1MEN1KMT2AKIF11 | |
| SCHEMBL8588813 | 0.83 | CA12 (0.42) | CA12CA1CA9CA2ALDH1A1 | |
| SCHEMBL8584956 | 0.82 | EPHX2 (0.38) | CA12CA1CA9CA2GRIA4 | |
| SCHEMBL8640045 | 0.82 | GRIA4 (0.41) | CA12CA1CA9CA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |