Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.45 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19469685 | 0.91 | CYP19A1 (0.49) | CHRNA7HTR2AHTR2CHTR2BMTNR1B | |
| SCHEMBL9521714 | 0.88 | CHRNA7 (0.47) | CHRNA7HTR2CGID4SIGMAR1CYP19A1 | |
| SCHEMBL3161060 | 0.81 | OPRM1 (0.44) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL7439467 | 0.81 | OPRM1 (0.44) | HTR2AHTR2CHTR2BMTNR1BMTNR1A | |
| SCHEMBL14199686 | 0.78 | MTNR1A (0.53) | MTNR1BMTNR1ASIGMAR1NQO2 | |
| SCHEMBL385632 | 0.78 | CYP19A1 (0.49) | CHRNA7HTR2CMTNR1BMTNR1ACYP19A1 | |
| SCHEMBL9814142 | 0.78 | CHRNA7 (0.44) | CHRNA7MAOAMEN1KMT2A | |
| SCHEMBL13306289 | 0.78 | HTR2C (0.62) | CHRNA7KDM1AMAOAMAOBHTR2A | |
| SCHEMBL29588202 | 0.78 | HTR2C (0.62) | CHRNA7KDM1AMAOAMAOBHTR2A | |
| SCHEMBL2970487 | 0.78 | HTR2C (0.62) | CHRNA7KDM1AMAOAMAOBHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |