Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586713 | 1.00 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8642502 | 0.94 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL8642508 | 0.94 | SIGMAR1 (0.36) | SIGMAR1 | |
| SCHEMBL8641584 | 0.87 | KDM1A (0.34) | SIGMAR1 | |
| SCHEMBL8589639 | 0.84 | BACE1 (0.30) | — | |
| SCHEMBL8589641 | 0.84 | BACE1 (0.30) | — | |
| SCHEMBL8615164 | 0.83 | BACE1 (0.32) | SIGMAR1 | |
| SCHEMBL8620702 | 0.81 | CYP2C9 (0.34) | SIGMAR1 | |
| SCHEMBL8636783 | 0.77 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL8612915 | 0.72 | ABL1 (0.34) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |