Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.33 |
| ▸ | POLA1 | P09884 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8615164 | 0.77 | BACE1 (0.32) | SIGMAR1 | |
| SCHEMBL8620702 | 0.77 | CYP2C9 (0.34) | ABL1MTNR1AMTNR1BFFAR1SIGMAR1 | |
| SCHEMBL8617783 | 0.74 | MTNR1A (0.39) | MTNR1AMTNR1B | |
| SCHEMBL8589639 | 0.73 | BACE1 (0.30) | — | |
| SCHEMBL8589641 | 0.73 | BACE1 (0.30) | — | |
| SCHEMBL8647745 | 0.73 | MAPK1 (0.39) | MTNR1AMTNR1BFFAR1 | |
| SCHEMBL8636783 | 0.73 | SIGMAR1 (0.39) | SIGMAR1 | |
| SCHEMBL8586713 | 0.72 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL8586706 | 0.72 | SIGMAR1 (0.31) | SIGMAR1 | |
| SCHEMBL13424190 | 0.72 | TSHR (0.32) | ABL1POLA1PPARGSMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052913-A2 | LEUKOTRIENE B4 ANTAGONISTS, IN PARTICULAR 3-OXA-TETRAHYDRONAPHTHALENE-LTB4 ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-11-26 | — | — | WO | disclosed |