SCHEMBL8586743

SCHEMBL8586743

C=CCc1cc[c]c(Cc2ccccc2)c1C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP19A1 P11511 1/20 0.33
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14692733 0.73 GABRA1 (0.43) KDM4EMEN1ALDH1A1LMNAKMT2A
SCHEMBL7141363 0.69 GABRA1 (0.41) KDM4EMEN1ALDH1A1LMNAKMT2A
SCHEMBL27938196 0.69 ADORA3 (0.35) MEN1ALDH1A1KMT2ARAB9ANPSR1
SCHEMBL9797619 0.69 ALDH1A1 (0.42) KDM4EALDH1A1KMT2A
SCHEMBL491175 0.68 GABRA1 (0.46) KDM4EMEN1ALDH1A1LMNAKMT2A
SCHEMBL27919603 0.68 GABRA1 (0.39) KDM4EALDH1A1LMNAKMT2A
SCHEMBL7751942 0.68 GABRA1 (0.39) KDM4EALDH1A1
Allylbenzene SCHEMBL793624 0.68 SLC18A3 (0.45) MEN1ALDH1A1KMT2A
SCHEMBL27631593 0.67 GABRA1 (0.38) KDM4EMEN1ALDH1A1KMT2A
SCHEMBL27927530 0.67 ABCB1 (0.44) KDM4EMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998017640-A1 HYDROGEN PEROXIDE ADDUCTS SOLVAY INTEROX LIMITED (GB) 1998-04-30 WO claimed