Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737105 | 0.97 | MAPT (0.61) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL7542589 | 0.88 | CTNNB1 (0.47) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL10390477 | 0.88 | AKR1C3 (0.60) | MAPTGAAAKR1C3POLBSRD5A2 | |
| SCHEMBL28482644 | 0.87 | CTNNB1 (0.46) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL31372448 | 0.87 | CTNNB1 (0.46) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL310144 | 0.85 | PBRM1 (0.50) | MAPTGAAPOLBMCL1ALDH1A1 | |
| SCHEMBL8586971 | 0.84 | MAPT (0.46) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL21808151 | 0.84 | MAPT (0.51) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL9063955 | 0.82 | POLB (0.50) | MAPTGAACCNE2CCNE1CDK2 | |
| SCHEMBL8974224 | 0.82 | CTNNB1 (0.46) | MAPTGAACCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026872-A | Intermediates, curing agents for polyepoxides | AMERICAN CYANAMID (US) | 1991-06-25 | — | — | US | disclosed |