Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121460 | 0.88 | LMNA (0.51) | HDAC4MEF2DGRIA1HDAC3HDAC1 | |
| SCHEMBL1133842 | 0.88 | LMNA (0.51) | HDAC4MEF2DGRIA1HDAC3HDAC1 | |
| SCHEMBL210916 | 0.88 | LMNA (0.51) | HDAC4MEF2DGRIA1HDAC3HDAC1 | |
| SCHEMBL10336284 | 0.85 | LMNA (0.52) | HDAC4MEF2DGRIA1HDAC3HDAC1 | |
| SCHEMBL10336285 | 0.85 | LMNA (0.52) | HDAC4MEF2DGRIA1HDAC3HDAC1 | |
| SCHEMBL30038001 | 0.82 | KDM4E (0.64) | FOLH1KDM4EHPGDHDAC1HDAC6 | |
| SCHEMBL2230077 | 0.82 | KDM4E (0.64) | FOLH1KDM4EHPGDHDAC1HDAC6 | |
| SCHEMBL8006880 | 0.79 | ERAP2 (0.52) | HDAC4MEF2DERAP2LNPEPERAP1 | |
| SCHEMBL30036662 | 0.78 | CA2 (0.56) | KDM4EHPGDHDAC1HDAC6LMNA | |
| SCHEMBL7415827 | 0.77 | GRIA1 (0.52) | HDAC4MEF2DGRIA1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998042730-A1 | SUBSTRATES USEFUL IN BOTH AQUEOUS AND ORGANIC MEDIA, AND ASSOCIATED METHODS OF PREPARATION AND USE | CHIRON CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |