Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592298 | 0.85 | L3MBTL3 (0.36) | L3MBTL3HRH3SLC6A4PIK3C3SIGMAR1 | |
| SCHEMBL8542700 | 0.83 | ATM (0.44) | HRH3SIGMAR1ALDH1A1NPC1USP2 | |
| SCHEMBL8542014 | 0.80 | SMN1; SMN2 (0.50) | HRH3SLC6A4ALDH1A1TSHR | |
| SCHEMBL25378330 | 0.77 | CHRNB2 (0.36) | SIGMAR1CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL30866563 | 0.76 | ALDH1A1 (0.57) | HRH3SLC6A4ALDH1A1HPGDCHRNB2 | |
| SCHEMBL9674112 | 0.76 | ALDH1A1 (0.57) | HRH3SLC6A4ALDH1A1HPGDCHRNB2 | |
| SCHEMBL9674102 | 0.76 | ALDH1A1 (0.57) | HRH3SLC6A4ALDH1A1HPGDCHRNB2 | |
| SCHEMBL9674105 | 0.76 | ALDH1A1 (0.57) | HRH3SLC6A4ALDH1A1HPGDCHRNB2 | |
| SCHEMBL8539303 | 0.76 | DRD3 (0.47) | SIGMAR1 | |
| SCHEMBL8544484 | 0.74 | CHRM2 (0.41) | L3MBTL3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0671388-B1 | (Pyrrolidinyl)phenyl carbamates and intermediate compounds, processes for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-06-10 | — | — | EP | claimed |