Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.51 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3399635 | 0.86 | CPA3 (0.49) | KIF11KEAP1 | |
| SCHEMBL8403280 | 0.84 | KIF11 (0.48) | KIF11HTTMEN1KMT2AKCNH2 | |
| SCHEMBL10586379 | 0.82 | KIF11 (0.54) | KIF11KCNH2 | |
| SCHEMBL3496480 | 0.80 | KIF11 (0.54) | KIF11HTTKMT2AKCNH2 | |
| SCHEMBL5065127 | 0.80 | KIF11 (0.45) | KIF11HTTMEN1KMT2AKCNH2 | |
| SCHEMBL14937220 | 0.79 | KIF11 (0.46) | KIF11HTTKMT2AKCNH2 | |
| SCHEMBL8734433 | 0.79 | KIF11 (0.44) | KIF11HTTMEN1KMT2AKCNH2 | |
| SCHEMBL7747362 | 0.79 | KIF11 (0.44) | KIF11HTTMEN1KMT2AKCNH2 | |
| SCHEMBL4579061 | 0.79 | KIF11 (0.44) | KIF11HTTMEN1KMT2AKCNH2 | |
| SCHEMBL5023008 | 0.78 | KIF11 (0.56) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140493-A | BIFUNCTIONAL SOLID SUPPORT HAVING A PLURALITY OF AMINE ACTIVE SITES AND A PLURALITY OF HYDROXYL ACTIVE SITES; FOR SOLID PHASE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (GB) | 2000-10-31 | — | — | US | claimed |