Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | MMP13 | P45452 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16104509 | 0.76 | CYP17A1 (0.53) | GRIA4CYP17A1CYP11B1CYP11B2KCNH2 | |
| SCHEMBL3532040 | 0.75 | CA2 (0.56) | MMP8MMP12MMP13MEN1KMT2A | |
| SCHEMBL8907383 | 0.75 | MEN1 (0.60) | MMP8MMP12MMP13MEN1KMT2A | |
| SCHEMBL5878462 | 0.74 | GRIA4 (0.64) | GRIA4CNR1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL8587459 | 0.73 | GRIA4 (0.44) | GRIA4CNR1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL28244556 | 0.73 | RARB (0.50) | CYP17A1CYP11B1CYP11B2HRH3KDM4E | |
| SCHEMBL8586492 | 0.73 | F10 (0.41) | GRIA4MMP8MMP12MMP13MEN1 | |
| SCHEMBL5877861 | 0.72 | GRIA4 (0.45) | GRIA4CNR1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL5877345 | 0.72 | GRIA4 (0.61) | GRIA4CNR1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL8587579 | 0.72 | ESR1 (0.44) | GRIA4GSK3BGRIA2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998033496-A1 | SULPHONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-08-06 | — | — | WO | disclosed |