Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 8/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26997345 | 0.81 | NCF1 (0.52) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL26997351 | 0.77 | DHODH (0.58) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL27560291 | 0.75 | DHODH (0.44) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL8587249 | 0.75 | IDO1 (0.45) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL26997362 | 0.73 | KDM4E (0.55) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL26997358 | 0.72 | KDM4E (0.56) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL5800340 | 0.72 | CYP19A1 (0.74) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL26998341 | 0.71 | CGAS (0.51) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL18292529 | 0.71 | CYP3A4 (0.55) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 | |
| SCHEMBL23116496 | 0.70 | CYP11B1 (0.52) | CYP3A4CYP1A2LMNACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | CYP3A4 1291/4885CYP1A2 1595/4885LMNA 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.