Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357513 | 0.91 | TSHR (0.39) | TSHRALOX15POLBAGTR2KDM4E | |
| SCHEMBL8364350 | 0.90 | TSHR (0.38) | TSHRALOX15POLBKDM4ELMNA | |
| SCHEMBL8361981 | 0.85 | PTPN11 (0.37) | TP53KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8417426 | 0.85 | TSHR (0.37) | TSHRALOX15POLBAGTR2 | |
| SCHEMBL8357460 | 0.84 | TSHR (0.38) | TSHRALOX15POLBAGTR2KDM4E | |
| SCHEMBL8359536 | 0.83 | KDM4E (0.40) | ALOX15AGTR2TP53KDM4ELMNA | |
| SCHEMBL8356863 | 0.81 | ALOX15 (0.38) | TSHRALOX15AGTR2TP53KDM4E | |
| SCHEMBL8361978 | 0.80 | PLA2G2A (0.36) | AGTR2PDE5A | |
| SCHEMBL8417957 | 0.79 | ALOX15 (0.41) | ALOX15POLBAGTR2TP53KDM4E | |
| SCHEMBL8359387 | 0.78 | TSHR (0.38) | TSHRALOX15POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736555-A | HYPOTENSIVE AGENTS; FDA ORANGE BOOK LISTED PATENT FOR AZILSARTAN MEDOXOMIL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-04-07 | — | — | US | disclosed |