1-Naphthol

1-Naphthol

SCHEMBL558316

COC.Oc1cccc2ccccc12

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.81
PTPN22 Q9Y2R2 1/20 0.48
IDO1 P14902 1/20 0.48
PLAU P00749 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MAPKAPK2 P49137 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
NQO2 P16083 1/20 0.46
TSHR P16473 3/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP2A6 P11509 2/20 0.46
MAPT P10636 2/20 0.46
APP P05067 1/20 0.46
THRB P10828 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
CASP1 P29466 1/20 0.46
SNCA P37840 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Naphthol SCHEMBL28636901 0.91 CYP1A2 (0.74) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL10627914 0.90 CYP1A2 (0.90) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL3416 0.90 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL29767730 0.90 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL273260 0.90 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL10486461 0.90 CYP1A2 (1.00) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL29209223 0.88 CYP1A2 (0.85) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL5336584 0.88 CYP1A2 (0.85) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL11295882 0.87 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E
1-Naphthol SCHEMBL9850314 0.87 CYP1A2 (0.94) CYP1A2PTPN22IDO1PLAUKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010954-A1 LAUNDRY DETERGENT COMPOSITION CONTAINING GRAFT COPOLYMER AND BENEFIT AGENT THE PROCTER & GAMBLE COMPANY 2024-01-11 US claimed
US-20220002632-A1 APPARATUS AND COMPOSITIONS FOR IMPROVING SCENT DELIVERY THE PROCTER AND GAMBLE COMPANY 2022-01-06 US claimed
US-20220002633-A1 APPARATUS AND COMPOSITIONS FOR IMPROVING SCENT DELIVERY THE PROCTER AND GAMBLE COMPANY 2022-01-06 US claimed
EP-3541913-A1 FABRIC TREATMENT COMPOSITIONS AND METHODS FOR PROVIDING A BENEFIT The Procter and Gamble Company (US) 2019-09-25 EP claimed
US-20190264142-A1 FABRIC TREATMENT COMPOSITIONS AND METHODS FOR PROVIDING A BENEFIT THE PROCTER & GAMBLE COMPANY 2019-08-29 US claimed
US-20190209441-A1 GEL NETWORK HAIR TREATMENT COMPOSITIONS WITH REDUCED ODOR WELLA OPERATIONS US, LLC 2019-07-11 US claimed
US-20190175476-A1 HAIR COLORING OR BLEACHING COMPOSITION WITH REDUCED ODOR WELLA OPERATIONS US, LLC 2019-06-13 US claimed
EP-3411465-A1 COMPOSITIONS CONTAINING ANTIFOAMS The Procter and Gamble Company (US) 2018-12-12 EP claimed
EP-3411425-A1 ANTIFOAM MOLECULES AND COMPOSITIONS The Procter and Gamble Company (US) 2018-12-12 EP claimed
WO-2018093758-A1 FABRIC TREATMENT COMPOSITIONS AND METHODS FOR PROVIDING A BENEFIT THE PROCTER & GAMBLE COMPANY (US) 2018-05-24 WO claimed
EP-1280882-A1 HIGHLY CONCENTRATED FABRIC SOFTENER COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2003-02-05 EP claimed
US-20020176879-A1 SKIN DEODORIZING COMPOSITIONS PROCTER & GAMBLE COMPANY, THE 2002-11-28 US claimed
WO-2002089862-A2 AIR FRESHENING COMPOSITIONS, ARTICLES COMPRISING SAME AND METHODS FOR PREPARING SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090479-A1 PERFUMED PARTICLES AND ARTICLES CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
WO-2002090481-A1 COMPOSITIONS AND ARTICLES FOR EFFECTIVE DEPOSITION OF PERFUME THE PROCTER & GAMBLE COMPANY (US) 2002-11-14 WO claimed
US-6344218-B1 GEL COMPRISING ODOR CONTROLLING AGENT TO PROVIDE ODOR CONTROL BENEFIT, SANITIZING AGENT, THICKENER, EMOLLIENT, PERFUME, WATER THE PROCTER & GAMBLE COMPANY 2002-02-05 US claimed
US-20020013234-A1 Fabric care compositions and systems for delivering clean, fresh scent in a lipophilic fluid treatment process PROCTER & GAMBLE COMPANY, THE 2002-01-31 US claimed
WO-2001094521-A1 FABRIC CARE COMPOSITIONS AND SYSTEMS FOR DELIVERING CLEAN, FRESH SCENT IN A LIPOPHILIC FLUID TREATMENT PROCESS THE PROCTER & GAMBLE COMPANY (US) 2001-12-13 WO claimed
WO-2001085892-A1 HIGHLY CONCENTRATED FABRIC SOFTENER COMPOSITIONS AND ARTICLES CONTAINING SUCH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-11-15 WO claimed
WO-2001085888-A2 LAUNDRY SYSTEM HAVING UNITIZED DOSING THE PROCTER & GAMBLE COMPANY (US) 2001-11-15 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020176879-A1 SKIN DEODORIZING COMPOSITIONS OR10J3, DSG1, OR51E2 CYP1A2 1197/4885PTPN22 1841/4885IDO1 648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.