Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589538 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL8586122 | 0.78 | PGK1 (0.32) | — | |
| SCHEMBL9816654 | 0.78 | SRC (0.38) | GSK3BGAAHPGDSMN1; SMN2ATM | |
| SCHEMBL11248883 | 0.75 | GSK3B (0.33) | GSK3B | |
| SCHEMBL8588544 | 0.70 | PGK1 (0.33) | — | |
| SCHEMBL8589342 | 0.64 | CYP2C19 (0.33) | SMN1; SMN2 | |
| SCHEMBL8587465 | 0.63 | PTPRC (0.30) | — | |
| SCHEMBL10804734 | 0.62 | HPGD (0.41) | GSK3BGAAHPGDSMN1; SMN2 | |
| SCHEMBL8588512 | 0.62 | ALOX5 (0.41) | GSK3BGAAATM | |
| SCHEMBL8587108 | 0.62 | HDAC6 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594857-B1 | METHANEDIPHOSPHONIC ACID DERIVATIVE, PRODUCTION THEREOF AND MEDICINAL USE THEREOF | TORAY INDUSTRIES (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5683992-A | TREATMENT OF RHEUMATISM, BONE DISORDERS, ANTIINFLAMMATORY, SUPPRESSION OF INTERLEUKIN-1, ANTIOXIDANT, TREATMENT OF AUTOIMMUNE DISEASES | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5527940-A | SUPPRESSES INTERLEUKIN-1 AND BONE DESTRUCTION DURING OSTEOPOROSIS; ANTIINFLAMMATORY AGENTS | TORAY INDUSTRIES, INC. (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0594857-A1 | METHANEDIPHOSPHONIC ACID DERIVATIVE, PRODUCTION THEREOF AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1994-05-04 | — | — | EP | disclosed |