Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1F | P30939 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8636423 | 0.87 | HTR1F (0.54) | NPC1RAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL8639560 | 0.87 | EPHX2 (0.45) | NPC1RAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL8584266 | 0.86 | HDAC3 (0.48) | CCNA2CDK2CCNA1HDAC3HDAC4 | |
| SCHEMBL8586359 | 0.86 | HTR1F (0.53) | NPC1RAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL8586794 | 0.83 | HTR1A (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8584947 | 0.81 | HTR1A (0.58) | HTR1AHTR1FHTR1BHCN1 | |
| SCHEMBL8585175 | 0.81 | HTR1A (0.46) | NPC1RAB9AHTR1AHTR1FKDM1A | |
| SCHEMBL8584756 | 0.78 | HTR1D (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8586100 | 0.77 | HTR1D (0.41) | HTR1AHTR1FPOLBALDH1A1HTR1D | |
| SCHEMBL8587381 | 0.76 | HTR1A (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |