Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 14/20 | 0.41 |
| ▸ | HTR1B | P28222 | 14/20 | 0.41 |
| ▸ | HTR1F | P30939 | 7/20 | 0.41 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8585944 | 0.83 | HTR1F (0.42) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8584756 | 0.82 | HTR1D (0.51) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL8584615 | 0.81 | HTR1A (0.56) | HTR1DHTR1BHTR1FHTR1AKDM4E | |
| SCHEMBL8585018 | 0.81 | HTR1D (0.40) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8586359 | 0.81 | HTR1F (0.53) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8636423 | 0.80 | HTR1F (0.54) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8584266 | 0.79 | HDAC3 (0.48) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL7778382 | 0.79 | HTR1D (0.50) | HTR1DHTR1BHTR1FHTR1AHTR2A | |
| SCHEMBL8587381 | 0.78 | HTR1A (0.56) | HTR1DHTR1BHTR1FHTR1A | |
| SCHEMBL8583475 | 0.78 | HTR1A (0.46) | HTR1DHTR1BHTR1FHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998020875-A1 | 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-05-22 | — | — | WO | disclosed |