SCHEMBL8588190

SCHEMBL8588190

C=CC[Sn](CC=C)(CC=C)c1ncccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6072984 0.74 MEN1 (0.37)
SCHEMBL4619452 0.63 ALDH1A1 (0.36)
SCHEMBL175905 0.62
SCHEMBL6158976 0.60 KDM4E (0.31)
SCHEMBL5140347 0.59
SCHEMBL3261534 0.59 CRHR1 (0.36)
SCHEMBL8177565 0.59 MAPT (0.41)
SCHEMBL5807783 0.58 ALDH1A1 (0.38)
Water SCHEMBL8664079 0.57
SCHEMBL2163151 0.57 ALDH1A1 (0.54)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180282347-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-10-04 US disclosed
US-20170265474-A1 BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2017-09-21 US disclosed
US-5720935-A CONTACTING IN AQUEOUS SOLUTION A RADIOACTIVE CHLORINE, BROMINE, IODINE OR ASTATINE ION, STANNYLATED PYRIMIDINE NUCLEOSIDE OR NUCLOTIDE, AN ACIDIC HYDROGEN PEROXIDE OXIDIZER, RADIOLABELLING BY DESTANYLATION PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) 1998-02-24 US disclosed
WO-1996041648-A1 RAPID SYNTHESIS OF RADIOLABELED PYRIMIDINE NUCLEOSIDES OR NUCLEOTIDES FROM STANNYL PRECURSORS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1996-12-27 WO disclosed