SCHEMBL2163151

SCHEMBL2163151

C=CCNc1ncccn1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
SLC2A1 P11166 1/20 0.44
SUMO3 P55854 1/20 0.43
SUMO2 P61956 1/20 0.43
SUMO1 P63165 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.42
KMT2A Q03164 2/20 0.42
GAA P10253 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 2/20 0.39
RRM2 P31350 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
HIF1A Q16665 1/20 0.39
HPGD P15428 2/20 0.38
MAPK1 P28482 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88752 0.79 MAPT (0.41) ALDH1A1SMN1; SMN2KMT2AGAAMAPT
SCHEMBL20523586 0.77 ALDH1A1 (0.39) ALDH1A1SLC2A1SUMO3SUMO2SUMO1
SCHEMBL1853374 0.76 INSR (0.43) ALDH1A1SMN1; SMN2KMT2AGAAMAPT
SCHEMBL1839657 0.76 SLC2A1 (0.44) ALDH1A1SLC2A1SUMO3SUMO2SUMO1
SCHEMBL9542185 0.76 GAA (0.33) ALDH1A1SLC2A1SUMO3SUMO2SUMO1
SCHEMBL369672 0.74 MAPT (0.44) ALDH1A1SMN1; SMN2KMT2AGAAMAPT
SCHEMBL10866005 0.74 KMT2A (0.39) ALDH1A1SLC2A1SUMO3SUMO2SUMO1
SCHEMBL3316097 0.74 MAPK13 (0.41) ALDH1A1SLC2A1SUMO3SUMO2SUMO1
SCHEMBL3320381 0.74 KMT2A (0.46) ALDH1A1SLC2A1SUMO3SUMO2SUMO1
SCHEMBL1002291 0.74 SLC2A1 (0.58) ALDH1A1SLC2A1SUMO3SUMO2SUMO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119069808-A Overcharge-preventing electrolyte additive and application thereof in sodium ion battery 浙江山高新能源有限公司 2024-12-03 CN claimed
CN-113164618-A Methods and compositions for treating diseases with immunostimulatory conjugates 希沃尔拜克治疗公司 2021-07-23 CN claimed
CN-100441228-C Use of substituted 2,4-bis (alkylamino) pyrimidines or -quinazolines as antimicrobials CIBA SC HOLDING AG (CH) 2008-12-10 CN claimed
CN-1829538-A Use of substituted 2, 4-bis (alkylamino) pyrimidines or-quinazolines as antibacterial agents CIBA SC HOLDING AG (CH) 2006-09-06 CN claimed
EP-0644882-A1 NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1995-03-29 EP claimed
WO-1993025539-A1 NOVEL PIPERZINYL-BIS(ALKYLAMINO)PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING SAME Richter Gedeon Vegyészeti Gyár Rt. (HU) 1993-12-23 WO claimed
EP-0411634-A2 Aminopyrimidine derivatives, preparation thereof and harmful organisms preventive agent UBE INDUSTRIES, LTD. (JP) 1991-02-06 EP claimed
JP-11139909-A None JP disclosed
JP-5230036-A None JP disclosed
JP-7033749-A None JP disclosed
CN-119069808-A Overcharge-preventing electrolyte additive and application thereof in sodium ion battery 浙江山高新能源有限公司 2024-12-03 CN disclosed
US-20240209015-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES ILLUMINA, INC. 2024-06-27 US disclosed
WO-2024137765-A1 TRANSITION-METAL CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS ILLUMINA, INC. (US) 2024-06-27 WO disclosed
US-4371391-A TRIAZIN-2-YL-AMINO CARBONYL BENZENE SURLONAMIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-02-01 US disclosed
US-4339266-A Herbicidal sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-07-13 US disclosed
EP-0048143-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1982-03-24 EP disclosed
EP-0036835-A1 Process for the preparation of metal complexes of isoindoline azines CIBA-GEIGY AG (CH) 1981-09-30 EP disclosed
US-4266057-A Process for the preparation of 2-isopropylamino pyrimidine EXPANSIA (FR) 1981-05-05 US disclosed
US-4257802-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-03-24 US disclosed
EP-0001514-A2 Herbicidal sulfonamides, and preparation and use thereof E.I. DU PONT DE NEMOURS AND COMPANY (US) 1979-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240209015-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES RNGTT, NT5C3B, NSUN2 ALDH1A1 879/4885SLC2A1 2850/4885SUMO3 4569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.