Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873723 | 0.91 | ESR2 (0.34) | ESR2AGTR1AGTR2NR3C1GPR119 | |
| SCHEMBL9016501 | 0.87 | AGTR1 (0.37) | ESR2AGTR1AGTR2NR3C1GPR119 | |
| SCHEMBL8872253 | 0.85 | AGTR1 (0.43) | ESR2AGTR1AGTR2NR3C1PPARG | |
| SCHEMBL9016524 | 0.81 | PPARG (0.41) | ESR2AGTR1NR3C1PPARGTRPA1 | |
| SCHEMBL9016407 | 0.79 | ALDH1A1 (0.38) | AGTR1AGTR2PPARGCYP1A2CYP2C19 | |
| SCHEMBL9016422 | 0.79 | PPARG (0.48) | ESR2AGTR1AGTR2NR3C1PPARG | |
| SCHEMBL8363423 | 0.77 | AGTR1 (0.32) | AGTR1AGTR2PPARG | |
| SCHEMBL8359446 | 0.77 | AGTR1 (0.33) | AGTR1AGTR2PPARG | |
| SCHEMBL8588243 | 0.77 | AGTR1 (0.34) | AGTR1AGTR2PPARG | |
| SCHEMBL8356866 | 0.77 | AGTR1 (0.34) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554757-A | Process for the preparation of imidazopyridine derivatives, and intermediates therefore | EISAI CO., LTD. (JP) | 1996-09-10 | — | — | US | disclosed |