Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.40 |
| ▸ | GRM6 | O15303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630748 | 0.78 | CYP2D6 (0.61) | CYP2D6SMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6543346 | 0.77 | CYP2D6 (0.59) | CYP2D6SMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL14000284 | 0.75 | LMNA (0.48) | LMNACYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8876545 | 0.73 | SIGMAR1 (0.56) | LMNACYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8592012 | 0.72 | GRM6 (0.38) | LMNACYP2D6GRM6SMN1; SMN2ALDH1A1 | |
| SCHEMBL31117994 | 0.71 | MEN1 (0.45) | LMNAALDH1A1KDM4EGAAMEN1 | |
| SCHEMBL14279455 | 0.70 | LMNA (0.42) | LMNACYP2D6SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4631263 | 0.69 | CYP2D6 (0.56) | CYP2D6SMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8877723 | 0.68 | CYP2D6 (0.57) | CYP2D6SMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL2700969 | 0.68 | CYP2D6 (0.58) | LMNACYP2D6ALDH1A1MAPK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712288-A | TACHYKININ ANTAGONIST, ANTIINFLAMMATORY, ANTIALLERGEN | SANOFI (FR) | 1998-01-27 | — | — | US | disclosed |