Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629950 | 0.80 | L3MBTL1 (0.53) | L3MBTL1HTTSMN1; SMN2SIGMAR1ALDH1A1 | |
| Bromide SCHEMBL7749201 | 0.79 | L3MBTL1 (0.52) | L3MBTL1HTTSMN1; SMN2SIGMAR1ALDH1A1 | |
| SCHEMBL8588940 | 0.72 | LMNA (0.41) | GRM6LMNAL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL4631263 | 0.67 | CYP2D6 (0.56) | L3MBTL1SMN1; SMN2SIGMAR1ALDH1A1CYP2D6 | |
| Hydrochloric Acid SCHEMBL20212096 | 0.66 | POLB (0.56) | L3MBTL1SMN1; SMN2SIGMAR1ALDH1A1GAA | |
| SCHEMBL4630748 | 0.65 | CYP2D6 (0.61) | L3MBTL1SMN1; SMN2ALDH1A1GAACYP2D6 | |
| SCHEMBL1771293 | 0.65 | KDM4E (0.53) | LMNAL3MBTL1ALDH1A1KDM4EGAA | |
| SCHEMBL18203100 | 0.65 | L3MBTL1 (0.63) | LMNAL3MBTL1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9768219 | 0.65 | GSK3B (0.44) | LMNASMN1; SMN2OPRM1ALDH1A1 | |
| SCHEMBL28041842 | 0.65 | RGS4 (0.41) | L3MBTL1SIGMAR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712288-A | TACHYKININ ANTAGONIST, ANTIINFLAMMATORY, ANTIALLERGEN | SANOFI (FR) | 1998-01-27 | — | — | US | disclosed |