Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AGXT | P21549 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | TPH1 | P17752 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8588435 | 0.87 | SIGMAR1 (0.51) | ALDH1A1AGXTSIGMAR1 | |
| SCHEMBL8589191 | 0.85 | ALDH1A1 (0.43) | MAOBALDH1A1MMESIGMAR1 | |
| SCHEMBL8587466 | 0.83 | KCNH2 (0.56) | ALDH1A1 | |
| SCHEMBL8587928 | 0.82 | DPP7 (0.47) | ALDH1A1ADAMTS5MMESIGMAR1 | |
| SCHEMBL8588118 | 0.82 | MC4R (0.43) | EPHX2ALDH1A1APP | |
| SCHEMBL8588129 | 0.82 | EPHX2 (0.44) | EPHX2MME | |
| SCHEMBL8589150 | 0.80 | TAAR1 (0.40) | MMESIGMAR1 | |
| SCHEMBL170305 | 0.79 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL21835602 | 0.79 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL10797644 | 0.79 | SIGMAR1 (0.55) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |