Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 7/20 | 0.35 |
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA9 | Q16790 | 6/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8304162 | 0.82 | CA1 (0.50) | MEN1KMT2ACA2CA1CA9 | |
| SCHEMBL10914174 | 0.80 | KMT2A (0.42) | MEN1KMT2ACA2CA1CA9 | |
| SCHEMBL28457469 | 0.80 | CA2 (0.40) | MEN1KMT2ACA2CA1CA9 | |
| SCHEMBL10922897 | 0.77 | MEN1 (0.36) | MEN1KMT2ACA2CA1CA9 | |
| SCHEMBL9775343 | 0.74 | KMT2A (0.39) | MEN1KMT2ACA2CA1CA9 | |
| Prosulfuron SCHEMBL56036 | 0.74 | MAPT (0.44) | CA2CA1CA9CA12 | |
| Prosulfuron SCHEMBL29440211 | 0.74 | MAPT (0.44) | CA2CA1CA9CA12 | |
| Prosulfuron SCHEMBL30298017 | 0.74 | MAPT (0.44) | CA2CA1CA9CA12 | |
| SCHEMBL9152873 | 0.73 | MEN1 (0.40) | MEN1KMT2ACA2CA1CA9 | |
| SCHEMBL30297961 | 0.71 | MEN1 (0.42) | MEN1KMT2ACA2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-H1711-H | SYNERGISTIC MIXTURE OF A PYRIMIDINYL-CONTAINING SULFONYL BENZOATE AND A TRIAZOLE-CONTAINING PHENYL METHANESULFONAMIDE | E. I. DU PONT (US) | 1998-02-03 | — | — | US | disclosed |