Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914174 | 0.85 | KMT2A (0.42) | KMT2ACA1CA2CA9MEN1 | |
| SCHEMBL8304162 | 0.82 | CA1 (0.50) | KMT2ACA1CA2CA9MEN1 | |
| SCHEMBL28457469 | 0.80 | CA2 (0.40) | KMT2ACA1CA2CA9MEN1 | |
| SCHEMBL11637514 | 0.79 | ALDH1A1 (0.47) | KMT2AMAPTSMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL10749518 | 0.76 | STAT3 (0.47) | KMT2AMAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL8303132 | 0.75 | ALDH1A1 (0.36) | KMT2AMAPTCA1CA2CA9 | |
| SCHEMBL8589747 | 0.74 | MEN1 (0.36) | KMT2ACA1CA2CA9MEN1 | |
| SCHEMBL2369909 | 0.74 | KMT2A (0.47) | KMT2AF2MAPTHPGDSMN1; SMN2 | |
| SCHEMBL10909928 | 0.74 | ALDH1A1 (0.45) | KMT2AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL10310551 | 0.72 | JAK2 (0.56) | KMT2AF2MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5013659-A | Hybrid to resist sulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-05-07 | — | — | US | disclosed |