⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3716933 | 0.77 | — | — | |
| SCHEMBL3723924 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL16992665 | 0.75 | DPP7 (0.33) | — | |
| SCHEMBL15955662 | 0.75 | DPP7 (0.38) | — | |
| SCHEMBL16335754 | 0.75 | DPP7 (0.38) | — | |
| SCHEMBL1821639 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL5201421 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL4054696 | 0.70 | CYP2D6 (0.32) | — | |
| SCHEMBL19924840 | 0.68 | GPR119 (0.32) | — | |
| SCHEMBL2916781 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499129-B1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2014-07-30 | — | — | EP | disclosed |
| US-20130012517-A1 | Quinoline and Quinoxaline Derivatives as Kinase Inhibitors | UCB PHARMA S.A. (BE) | 2013-01-10 | — | — | US | disclosed |
| EP-2499129-A1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2012-09-19 | — | — | EP | disclosed |
| WO-2011058108-A1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2011-05-19 | — | — | WO | disclosed |