SCHEMBL8590446

SCHEMBL8590446

Nc1nc(-c2ccccc2)[nH]c1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.61
ALDH1A1 P00352 5/20 0.61
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
HPGD P15428 3/20 0.61
SMN1; SMN2 Q16637 3/20 0.61
KDM4E B2RXH2 4/20 0.54
CASP6 P55212 1/20 0.54
PI4KA P42356 1/20 0.51
PI4K2B Q8TCG2 1/20 0.51
PI4K2A Q9BTU6 1/20 0.51
PI4KB Q9UBF8 1/20 0.51
HSD17B10 Q99714 2/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
KCNH2 Q12809 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
GAA P10253 4/20 0.49
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5383067 0.81 MEN1 (0.50) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL4066060 0.81 ALDH1A1 (0.59) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL8306285 0.79 MAPT (0.51) MAPTALDH1A1MEN1KMT2AHPGD
Hydrochloric Acid SCHEMBL27477043 0.78 MAPT (0.56) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL19233117 0.76 MAPT (0.59) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL2818111 0.76 MAPK14 (0.60) MEN1KMT2ASMN1; SMN2KDM4ENPC1
SCHEMBL13115559 0.76 MAPK14 (0.60) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL10723436 0.74 MEN1 (0.70) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL6691823 0.74 PIN1 (0.56) MAPTALDH1A1MEN1KMT2AHPGD
SCHEMBL29387115 0.74 PIN1 (0.56) MAPTALDH1A1MEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0677540-B1 Process for the preparation of polyurethane foams in the presence of amino alkyl or aminophenyl imidazoles as catalysts, as well as the use of these catalysts for the preparation of polyisocyanate-polyaddition products BASF AG (DE) 1999-01-27 EP claimed
EP-4314193-B1 STABLE AIGS FILMS SHOEI CHEMICAL IND CO (JP) 2025-10-15 EP disclosed
EP-4314193-A1 STABLE AIGS FILMS Shoei Chemical Inc. (JP) 2024-02-07 EP disclosed
CN-117396581-A Stable AIGS film 纳米系统公司 2024-01-12 CN disclosed
CN-116981754-A Film comprising bright silver-based quaternary nanostructures 纳米系统公司 2023-10-31 CN disclosed
WO-2022212517-A1 STABLE AIGS FILMS NANOSYS, INC. (US) 2022-10-06 WO disclosed