Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27461517 | 0.82 | NPC1 (0.57) | MAPTHSD17B10RPS6KA3MEN1KMT2A | |
| SCHEMBL647088 | 0.79 | PIN1 (0.59) | MAPTHSD17B10RPS6KA3GAAPOLB | |
| SCHEMBL8590446 | 0.79 | MAPT (0.61) | MAPTALOX15ALOX12KCNH2NPSR1 | |
| SCHEMBL5383067 | 0.78 | MEN1 (0.50) | MAPTALOX15ALOX12KCNH2NPSR1 | |
| SCHEMBL11516210 | 0.78 | MAPK13 (0.53) | MAPTRPS6KA3MEN1KMT2AGAA | |
| SCHEMBL8075160 | 0.76 | KDM4E (0.49) | MAPTHSD17B10RPS6KA3GAAALDH1A1 | |
| SCHEMBL547135 | 0.76 | PIN1 (0.56) | MAPTALOX15ALOX12KCNH2NPSR1 | |
| SCHEMBL13943652 | 0.76 | MAPT (0.49) | MAPTHSD17B10RPS6KA3MEN1KMT2A | |
| SCHEMBL18585937 | 0.76 | GAA (0.49) | MAPTHSD17B10RPS6KA3GAAHPGD | |
| Hydrochloric Acid SCHEMBL27477043 | 0.74 | MAPT (0.56) | MAPTRPS6KA3MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923573-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0923573-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| US-5905152-A | Preparation of aminomethyl-phenylimidazoles | SCHERING CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |
| US-5905152-A | Preparation of aminomethyl-phenylimidazoles | SCHERING CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |
| US-5905152-A | Preparation of aminomethyl-phenylimidazoles | SCHERING CORPORATION (US) | 1999-05-18 | — | — | US | disclosed |
| WO-1998006716-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |
| WO-1998006716-A1 | PREPARATION OF AMINOMETHYL-PHENYLIMIDAZOLES | SCHERING CORPORATION (US) | 1998-02-19 | — | — | WO | disclosed |